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| 1 | Acknowledgements
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| 2 | Preliminary Information
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| 2.1 | Restrictions and Disclaimer
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| Distribution Restrictions
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| General Disclaimer
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| How to Reach the Author
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| 2.2 | Why a DXM FAQ?
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| 2.3 | Keeping DXM Legal
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| 2.4 | How to Use This Document
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| 3 | DXM QuickFAQ
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| 3.1 | What is DXM?
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| 3.2 | You Mean I Can Get High Off Cough Syrup?
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| 3.3 | What Kinds of Cough Medicine are Safe?
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| 3.4 | What Happens if I Drink the Wrong Cough Syrup?
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| 3.5 | I'm Taking Other Drugs -- Can I Take DXM?
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| 3.6 | What's the DXM Trip Like?
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| 3.7 | How Much DXM Do I Take?
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| 3.8 | Is DXM Like Acid?
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| 3.9 | Is DXM Fun?
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| 3.10 | Is DXM Dangerous?
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| 3.11 | If DXM is Dangerous, Why Do It?
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| 4 | General Information About DXM
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| 4.1 | DXM Quick Reference Page
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| 4.2 | What is Dextromethorphan Hydrobromide (DXM)?
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| 4.3 | What is Dextromethorphan Polistirex?
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| 4.4 | What is Dextrorphan (DXO)?
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| 4.5 | Is DXM Enjoyable as a Recreational Drug?
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| 4.6 | Is DXM an Opiate?
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| 4.7 | Does Everyone Like DXM?
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| 4.8 | How Does One Obtain and Use DXM?
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| Cough Syrups
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| Gelcaps
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| Tablets and Capsules (including Coricidin)
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| Lozenges
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| Pharmaceutical and Chemical Suppliers
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| Extracted DXM
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| Injection and Other Routes
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| 4.9 | What are Some Typical DXM-Containing Preparations?
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| 4.10 | How am I Supposed to Drink Cough Syrup?
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| 4.11 | What Should I Know About Other Drug Ingredients?
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| Decongestants
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| Antihistamines
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| Guaifenesin
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| Analgesics, Acetaminophen/Paracetamol
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| Alcohol
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| Food Coloring and Dyes
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| Bromide Ions
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| Other "Inactive" Ingredients
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| 4.12 | Why are So Many DXM Preparations in Liquid Form?
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| 4.13 | Is Recreational Use of DXM Illegal?
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| 4.14 | If DXM is Legal Why Isn't Everyone Doing It?
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| 4.15 | New Medical Uses for DXM
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| Diagnostic Uses
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| Neuroprotectant Uses
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| DXM for Chronic Pain
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| DXM for Drug Addiction
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| DXM for Disease and Miscellaneous Conditions
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| 4.16 | Drug Interactions
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| Fatal or Dangerous Interactions
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| Beneficial Drug Interactions
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| Recreational Drug Interactions
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| 4.17 | General Warnings
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| 4.18 | What About Other Cough Suppressants?
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| Noscapine
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| Opiates
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| Topical Anaesthetics
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| Can DXM be Detected on Drug Tests?
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| 5 | The DXM Experience
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| 5.1 | What is the General Character of the DXM Experience?
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| 5.2 | Overview of the Lower Plateaus
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| 5.3 | The First Plateau
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| Sensory Effects
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| Cognitive/Emotional Effects
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| Motor Effects
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| Memory Effects
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| 5.4 | The Second Plateau
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| Sensory Effects
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| Cognitive/Emotional Effects
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| Motor Effects
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| Memory Effects
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| 5.5 | The Transitional Phase
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| 5.6 | The Upper Plateaus
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| 5.7 | The Third Plateau
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| Sensory Effects
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| Cognitive/Emotional Effects
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| Motor Effects
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| Memory Effects
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| 5.8 | The Fourth Plateau
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| 5.9 | Plateau Sigma
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| 5.10 | Is There Anything Beyond the Fourth Plateau?
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| 5.11 | What is the "DXM Third Eye Camera"?
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| 5.12 | Tussin Space, Tussin Consciousness
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| 5.13 | What is the "Tussin Euphoria" and What Makes it Unique?
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| 5.14 | What Can Happen with Long-term or Regular Use?
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| 5.15 | Why does DXM Affect Different People So Differently?
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| 5.16 | How Does DXM Compare With Other Dissociatives?
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| 6 | DXM Side Effects and Other Things to Avoid
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| 6.1 | What are Some Minor Risks of Occasional Use?
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| Nausea and Other Gastric Disturbances
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| Dizziness
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| Mild Allergic Reactions and Histamine Release
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| Sexual Dysfunction
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| Diaphoresis (sweating)
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| Impaired Judgement and Mental Performance
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| Hangovers
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| Tachycardia (Increased Heart Rate)
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| Pupil Dilation or Constriction
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| Hot and Cold Flashes
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| Facial Edema
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| Mild Hypertension (High Blood Pressure)
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| Mild Hyperthermia (Increased Temperature)
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| Overexertion
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| Urticaria (skin rash/wheal)
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| Increased Bile Secretion
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| Inappropriate Behaviour
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| Miscellaneous
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| 6.2 | What are Some Major Risks of Occasional Use?
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| Panic Attacks
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| Psychotic Breaks
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| Impaired Judgement in Critical Situations
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| Depression
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| Serious Hyperthermia (High Temperature)
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| Serious Hypertension (High Blood Pressure)
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| Rhabdomyolysis
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| Respiratory Depression
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| Serotonin Syndrome
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| Major Allergic Reactions and Histamine Release
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| Miscellaneous
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| 6.3 | What Are the Risks of Regular Use and Binges?
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| NMDA Antagonist Neurotoxicity (Olney's Lesions)
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| Cerebral Hemorrhage and Stroke
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| Other Neurotoxicity Mechanisms
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| Mania
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| Depression
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| Violent Ideations, Antisocial Behaviour, and Paranoia
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| Memory Impairment
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| Language Impairment
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| Weight Loss
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| Loss of Muscle Control
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| Habituation and Psychological Addiction
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| Tolerance and Physical Addiction
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| Psychosis
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| Liver, Kidney, and Pancreas Damage
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| Bromide Poisoning
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| Miscellaneous
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| Summary: Regular Use Considered
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| 6.4 | DXM and Pregnancy
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| 6.5 | What is NMDA Antagonist Neurotoxicity and How do I Prevent It?
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| Overview and Mechanism of Olney's Lesions
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| Dosages at Which NAN Occurs
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| Balancing the Risks: Is Olney's Research Relevant to DXM Use?
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| A Look at the Areas Involved
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| Preventing and Limiting NMDA Antagonist Neurotoxicity
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| 6.6 | Is DXM Addictive?
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| 6.7 | Is DXM Withdrawal Dangerous?
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| 6.8 | Kicking the DXM Habit: What to Do If You are Addicted
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| Preparing to Quit
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| Quitting "Cold Turkey"
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| Build-Down
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| After Quitting: When Can I Use DXM Again?
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| 6.9 | DXM Hangovers -- Avoiding and Alleviating
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| 6.10 | How Toxic is DXM, and What is the Lethal Dose?
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| 6.11 | Do You Recommend DXM for Recreational Use?
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| 6.12 | Help! What do I do if ...
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| Itching (the "Robo Itch")
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| Fast Heartbeat
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| Panic Attacks
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| Irregular or Skipped Heartbeats
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| Nausea, Vomiting, Gas, and Diarrhea
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| Unconsciousness
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| Overdose
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| High Temperature / Fever
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| Shortness of Breath / Breathing Problems
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| Choking On Your Tongue
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| Nosebleeds
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| Feeling "dead" / losing one's body
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| Hangovers (lethargy and feeling "not all there")
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| Prolonged Dissociation From the Real World
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| Serotonin Syndrome
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| Bad Trips
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| Psychotic Breaks
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| 6.13 | How to Know When You've Done Too Much DXM
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| 7 | Getting the Most Out of DXM
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| 7.1 | General Tips on Enjoying the DXM Experience
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| 7.2 | What are Some Fun or Interesting Things to Do on DXM?
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| Listen to Music
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| 7.3 | Watch a Movie
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| Make Music
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| Dance
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| Swimming (First Plateau Only!)
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| Group Tripping
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| Paranormal/Spiritual Exploration
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| Observe People
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| 7.4 | What Tools Can Enhance the DXM Experience?
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| Sensory Deprivation
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| Ganzfeld
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| Light and Sound (Brainwave) Machines
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| Hemisphere Synch Audio Tapes
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| Trip Programs
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| Trip Toys
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| 7.5 | What are Some Things to Avoid on DXM?
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| Heavy Exercise
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| Driving
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| Going to Class, School, or Work on DXM
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| Dose "Boosting" and Re-dosing
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| Stressful Environments
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| 7.6 | What is the "50 Trip Limit" and How Can I Avoid It?
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| 7.7 | Why Can't I Hallucinate on DXM?
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| 8 | Altered States and Paranormal Experiences
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| 8.1 | Preliminary Information and Discussion
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| 8.2 | What Paranormal and Altered State Experiences Occur on DXM?
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| The Dissociative Spiral
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| Deja Vu and Other Memory Mishaps
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| Out-of-Body Experiences (OOBEs)
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| Near-Death and Rebirth Experiences
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| Contact with Alien and Spiritual Beings
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| Clairvoyance, ESP, and Other Psi Phenomena
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| Memory Loops and Prescient Sensations
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| Dissociative Thought Patterns
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| 8.3 | Cosmic Coincidence Central and the Alien Conspiracy
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| 8.4 | Are These Experiences Dangerous?
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| 8.5 | How Can These Be Explained
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| Temporal Anomalies
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| Complex Partial Seizures
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| Influence of the Unseen Environment
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| Spiritual Explanations
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| 8.6 | How do I Maximize Altered States and Paranormal Experiences?
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| Theta Stimulation
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| Hemisphere Synch Tapes
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| Magnetic Stimulation
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| Sensory Deprivation and Ganzfeld
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| Predosing
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| Meditation
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| 8.7 | Factors Affecting Susceptibility to Paranormal Experiences
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| 8.8 | A Warning About "Spiritual Shortcuts"
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| 8.9 | A Warning About Temporal Lobe Epilepsy
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| 9 | Physiological Effects of DXM
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| 9.1 | How Does DXM Inhibit the Cough Reflex?
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| 9.2 | How Does DXM Cause its Psychoactive Effects?
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| General Information
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| Contribution of the PCP2 Binding Site
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| Contribution of the Sigma Binding Sites
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| Contribution of the NMDA Receptor
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| Temporal Lobe Involvement
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| Contributions of Indirect Activity
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| Flanging
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| Hyper-Abstraction
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| Delusions and Memory Problems
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| 9.3 | Why Does DXM Exhibit Plateaus?
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| Plateaus 1-3: Multiple Receptors
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| The Fourth Plateau: Sensory Shutdown
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| 9.4 | Why is This So Complicated?
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| 9.5 | Pharmacokinetics: How DXM is Metabolized
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| Factors Affecting Metabolism of DXM
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| 10 | Neuropharmacology of DXM
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| 10.1 | What is a Receptor, Anyway? (Basic Neuropharmacology)
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| The Structure of a Nerve Cell
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| Neurotransmission
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| 10.2 | What are Sigma Receptors?
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| Sigma 1 Receptors and General Sigma Information
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| Sigma 2 Receptors
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| Sigma 3 Receptors
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| 10.3 | What Are NMDA Receptors?
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| NMDA and Other Glutamate Receptors
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| NMDA Receptor Structure and Function
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| NMDA Receptors and Excitotoxicity
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| 10.4 | What are PCP2 Receptors?
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| 10.5 | What are Na+ and Ca2+ Channels?
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| 10.6 | How Does DXM Compare to Other Dissociatives at These Receptors?
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| 10.7 | Endopsychosin and the Big Picture
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| 11 | DXM Chemistry and Extraction
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| 11.1 | How Can I Extract DXM From Cough Syrups and Gelcaps?
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| Theory of Acid-Base Extractions
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| Single-Phase Acid-Base Extraction of DXM
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| Agent Lemon: Dual-Phase Acid-Base Extraction of DXM
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| Precipitation Method
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| 11.2 | How Can I Get Rid of Other Drug Ingredients?
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| Acetaminophen
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| Guaifenesin
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| Antihistamines and Decongestants
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| 11.3 | How Can I Test for Acetaminophen?
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| 11.4 | How do I Use Free Base DXM?
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| 11.5 | How Can I Synthesize DXM?
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| 11.6 | What Can I Synthesize From DXM?
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| Dextrorphan
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| Levorphanol / Levomethorphan
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| 3-Substituted Analogs
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| 12 | DXM Drug Culture
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| 12.1 | Is There, or Was There, a DXM Drug Culture?
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| DXM in the 1960's
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| DXM in the 1970's
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| DXM in the 1980's
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| DXM in the 1990's
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| The Future of DXM Use
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| 12.2 | Why Haven't I Heard About DXM Drug Culture?
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| 12.3 | DXM "Drug Slang"
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| Non-American DXM Drug Slang
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| 12.4 | How do I Tell My Friends I'm Getting High off Cough Syrup?
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| 13 | Mixing DXM and Other Drugs
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| 13.1 | Alcohol
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| 13.2 | Barbiturates and Benzodiazepines
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| 13.3 | Amphetamines and Other Psychostimulants
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| 13.4 | Cannabis (Marijuana)
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| 13.5 | LSD, Psilocybin (Shrooms), and Other 5HT Hallucinogens
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| 13.6 | Opiates
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| 13.7 | PCP and Ketamine
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| 13.8 | Nicotine
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| 13.9 | Phenethylamines (MDMA, MDA, 2CB, etc)
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| 13.10 | Nootropics (Smart Drugs)
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| 13.11 | Miscellaneous Other Drugs
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| 14 | DXM Experiences and Personal Reports
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| 14.1 | First and Second Plateau Experiences
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| Positive Experiences
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| Negative Experiences
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| 14.2 | Third and Fourth Plateau Experiences
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| Positive Experiences
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| Negative Experiences
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| 14.3 | Long Term Use Experiences
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| Positive Experiences
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| Negative Experiences
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| 14.4 | Multiple Drug Experiences
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| DXM + Cannabis + Alcohol + Opium
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| DXM + Cyclazine
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| DXM + Mushrooms + LSD + Cannabis + Nitrous Oxide
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| 15 | Appendices
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| 15.1 | Appendix 1: P450 Inhibiting Drugs
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| 15.2 | Appendix 2: Neuropharmacology of Recreational Drugs
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| 15.3 | Appendix 3: Other Sigma and NMDA Ligands
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| 16 | Glossary
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| 17 | References
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